USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P49454 USC-OGP 2-DE database:  P49454 P49454 General information about the entry View entry in simple text format Entry name CENPF_HUMAN Primary accession number P49454 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor;. Gene name Name=CENPF Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1121: pI=5.77; Mw=83686 Cross-references UniProtKB/Swiss-Prot P49454; CENPF_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CENPF_HUMAN Primary accession number P49454 Secondary accession number(s) Q13171 Q13246 Q5VVM7 Sequence was last modified on  August 21, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 172) Name and origin of the protein Description RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor; Gene name Name=CENPF Encoded on Name=CENPF Keywords Acetylation; Cell cycle; Cell division; Centromere; Chromosome; Ciliopathy; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Differentiation; DNA synthesis; Kinetochore; Lipoprotein; Methylation; Mitosis; Myogenesis; Nucleus; Phosphoprotein; Polymorphism; Prenylation; Primary ciliary dyskinesia; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U19769; AAA82889.1; -; mRNA EMBL U30872; AAA82935.1; -; mRNA EMBL AL445666; CAH71810.1; -; Genomic_DNA EMBL AL445305; CAH71810.1; JOINED; Genomic_DNA EMBL AL445305; CAH73032.1; -; Genomic_DNA EMBL AL445666; CAH73032.1; JOINED; Genomic_DNA EMBL BC172232; AAI72232.1; -; mRNA EMBL U25725; AAA86889.1; -; mRNA PIR PC4035; PC4035; . RefSeq NP_057427.3; NM_016343.3; . UniGene Hs.497741; -; . ProteinModelPortal P49454; -; . SMR P49454; -; . BioGrid 107492; 47; . IntAct P49454; 27; . MINT MINT-2803614; -; . STRING 9606.ENSP00000355922; -; . iPTMnet P49454; -; . PhosphoSitePlus P49454; -; . BioMuta CENPF; -; . DMDM 156630875; -; . EPD P49454; -; . MaxQB P49454; -; . PaxDb P49454; -; . PeptideAtlas P49454; -; . PRIDE P49454; -; . Ensembl ENST00000366955; ENSP00000355922; ENSG00000117724; . GeneID 1063; -; . KEGG hsa:1063; -; . UCSC uc001hkm.4; human; . CTD 1063; -; . DisGeNET 1063; -; . GeneCards CENPF; -; . H-InvDB HIX0028827; -; . HGNC HGNC:1857; CENPF; . HPA CAB009581; -; . HPA HPA052382; -; . MalaCards CENPF; -; . MIM 243605; phenotype; . MIM 600236; gene; . neXtProt NX_P49454; -; . PharmGKB PA26401; -; . eggNOG ENOG410IGJF; Eukaryota; . eggNOG ENOG410XS5F; LUCA; . HOVERGEN HBG050893; -; . InParanoid P49454; -; . KO K11499; -; . OrthoDB EOG091G01XR; -; . PhylomeDB P49454; -; . TreeFam TF101133; -; . Reactome R-HSA-156711; Polo-like kinase mediated events; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-68877; Mitotic Prometaphase; . ChiTaRS CENPF; human; . GeneWiki CENPF; -; . GenomeRNAi 1063; -; . PRO PR:P49454; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000117724; -; . CleanEx HS_CENPF; -; . ExpressionAtlas P49454; baseline and differential; . Genevisible P49454; HS; . GO GO:0005930; C:axoneme; IEA:Ensembl; . GO GO:0005813; C:centrosome; IEA:Ensembl; . GO GO:0000775; C:chromosome; centromeric region; IDA:UniProtKB GO GO:0036064; C:ciliary basal body; IEA:Ensembl; . GO GO:0097539; C:ciliary transition fiber; IMP:GO_Central; . GO GO:0000940; C:condensed chromosome outer kinetochore; IDA:UniProtKB; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0000776; C:kinetochore; IDA:UniProtKB; . GO GO:0030496; C:midbody; IDA:UniProtKB; . GO GO:0005635; C:nuclear envelope; IDA:UniProtKB; . GO GO:0016363; C:nuclear matrix; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell; . GO GO:0045120; C:pronucleus; IEA:Ensembl; . GO GO:0005819; C:spindle; IDA:UniProtKB; . GO GO:0000922; C:spindle pole; IDA:UniProtKB; . GO GO:0003682; F:chromatin binding; NAS:UniProtKB; . GO GO:0070840; F:dynein complex binding; IDA:UniProtKB; . GO GO:0008022; F:protein C-terminus binding; IPI:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IPI:UniProtKB; . GO GO:0008134; F:transcription factor binding; IPI:UniProtKB; . GO GO:0030154; P:cell differentiation; IEA:UniProtKB-KW; . GO GO:0051301; P:cell division; IEA:UniProtKB-KW; . GO GO:0008283; P:cell proliferation; NAS:UniProtKB; . GO GO:0007059; P:chromosome segregation; IMP:UniProtKB; . GO GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW; . GO GO:0001822; P:kidney development; IMP:GO_Central; . GO GO:0051382; P:kinetochore assembly; NAS:UniProtKB; . GO GO:0051310; P:metaphase plate congression; IDA:UniProtKB; . GO GO:0000278; P:mitotic cell cycle; IMP:UniProtKB; . GO GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW; . GO GO:0007094; P:mitotic spindle assembly checkpoint; NAS:UniProtKB; . GO GO:0007517; P:muscle organ development; IEA:UniProtKB-KW; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:0015031; P:protein transport; IDA:UniProtKB; . GO GO:0051726; P:regulation of cell cycle; TAS:Reactome; . GO GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB; . GO GO:0016202; P:regulation of striated muscle tissue development; ISS:UniProtKB; . GO GO:0042493; P:response to drug; NAS:UniProtKB; . GO GO:0007062; P:sister chromatid cohesion; TAS:Reactome; . GO GO:0021591; P:ventricular system development; IMP:GO_Central; . InterPro IPR018302; CenpF/LEK1_Rb-prot-bd; . InterPro IPR019513; Centromere_CenpF_leu-rich_rpt; . InterPro IPR018463; Centromere_CenpF_N; . Pfam PF10490; CENP-F_C_Rb_bdg; 1; . Pfam PF10473; CENP-F_leu_zip; 3; . Pfam PF10481; CENP-F_N; 1; .

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